ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Itgb1bp1

Full Name:

integrin beta 1 binding protein 1

Alias:

AI449260|AU019480|bodenin

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

12 A1.2

Physical Location:

21275666-21292097 on NC_000078.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9270 Symbol (Name): ITGB1BP1 (integrin beta 1 binding protein 1)

Ortholog Status:

The human GeneID 9270 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AJ001373
Note:		Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008403.4	NP_032429.1	NC_000078.5 range: 21275666..21292097, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005178	integrin binding	Molecular Function	ISO
GO:0008022	protein C-terminus binding	Molecular Function	ISO
GO:0007229	integrin-mediated signaling pathway	Biological Process	IEA
GO:0030155	regulation of cell adhesion	Biological Process	ISO