ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mpv17

Full Name:

Mpv17 transgene, kidney disease mutant

Alias:

Tg.Mpv17

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

5 B1

Physical Location:

31443320-31456603 on NC_000071.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4358 Symbol (Name): MPV17 (MpV17 mitochondrial inner membrane protein)

Ortholog Status:

The human GeneID 4358 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		M36411
Note:		Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008622.5	NP_032648.1	NC_000071.5 range: 31443320..31456603, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IMP (16582910)
GO:0005739	mitochondrion	Cellular Component	ISO
GO:0005777	peroxisome	Cellular Component	IDA (7957077)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0006800	oxygen and reactive oxygen species metabolic process	Biological Process	IDA (7957077)
GO:0007605	sensory perception of sound	Biological Process	IMP