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Gene Information
Gene ID:17527
Symbol:Mpv17
Full Name:Mpv17 transgene, kidney disease mutant
Alias:Tg.Mpv17
Organism:Mus musculus (Mouse)
Chromosome:5
Genetic Location:5 B1
Physical Location:31443320-31456603 on NC_000071.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 4358    Symbol (Name): MPV17 (MpV17 mitochondrial inner membrane protein)
Ortholog Status:The human GeneID 4358 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:M36411
Note:Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains
Dataset Information
Name:15282116
Method:Microarray
Tissue:Striata
Phenotype:Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_008622.5NP_032648.1NC_000071.5 range: 31443320..31456603, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentIMP (16582910)
GO:0005739mitochondrionCellular ComponentISO
GO:0005777peroxisomeCellular ComponentIDA (7957077)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0006800oxygen and reactive oxygen species metabolic processBiological ProcessIDA (7957077)
GO:0007605sensory perception of soundBiological ProcessIMP
Other Database Cross Links
NCBI Entrez Gene:17527
MGI:
Ensembl:ENSMUSG00000029144
dbSNP:Mpv17
AceView:Mpv17