ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Ybx1

Full Name:

Y box protein 1

Alias:

1700102N10Rik|C79409|EF1A|MGC118070|MSY1|Nsep1|YB-1|dbpB|mYB-1a

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D1

Physical Location:

118949931-118967117 on NC_000070.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4904 Symbol (Name): YBX1 (Y box binding protein 1)

Ortholog Status:

The human GeneID 4904 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		U33196
Note:		Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_011732.2	NP_035862.2	NC_000070.5 range: 118949931..118967117, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	RCA (16141072)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI (15596447)
GO:0003676	nucleic acid binding	Molecular Function	RCA (16141072)
GO:0003677	DNA binding	Molecular Function	RCA (16141072)
GO:0003697	single-stranded DNA binding	Molecular Function	IDA (15282343)
GO:0003723	RNA binding	Molecular Function	IEA
GO:0006397	mRNA processing	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	RCA (16141072)
GO:0006350	transcription	Biological Process	IEA
GO:0001701	in utero embryonic development	Biological Process	IGI (16954378)
GO:0001701	in utero embryonic development	Biological Process	IMP (16954378)
GO:0008380	RNA splicing	Biological Process	IEA