ERGR - Ethanol-Related Gene Resource

Dataset Description

Dataset Name: 15282116

Species: Mouse

No. of Genes: 56

Tissue: Striata

Phenotype: Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration

Publication: Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed

Dataset Summary: Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene list of this dataset (56 genes)
Page: 1 2 list all
GeneID Symbol Name Genetic location Original ID1 Original ID2
14296 Frat1 frequently rearranged in advanced T-cell lymphomas 19 C3|19 37.5 cM U58974
16573 Kif5b kinesin family member 5B 18 1.0 cM U86090
110454 Ly6a lymphocyte antigen 6 complex, locus A 15 D3|15 42.7 cM X04653
17025 Alad aminolevulinate, delta-, dehydratase 4 B3|4 30.6 cM X13752
19659 Rbp1 retinol binding protein 1, cellular 9 E3.3|9 52.0 cM X60367
14806 Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 10 B3|10 27.0 cM X66117
19941 Rpl26 ribosomal protein L26 11 B3 X80699
11815 Apod apolipoprotein D 16 B2|16 21.2 cM X82648
11482 Acvrl1 activin A receptor, type II-like 1 15 F3 Z31664
AA420337
12716 Ckmt1 creatine kinase, mitochondrial 1, ubiquitous 2 F1-F3|2 67.6 cM AV091448
17217 Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 16 B1|16 9.2 cM D26089
67231 Tbc1d20 TBC1 domain family, member 20 2 H1 AW121234
242785 Klhl21 kelch-like 21 (Drosophila) 4 E2 AI882440
AI847033
Page: 1 2 list all

GeneID	Symbol	Name	Genetic location	Original ID1	Original ID2
14296	Frat1	frequently rearranged in advanced T-cell lymphomas	19 C3\|19 37.5 cM	U58974
16573	Kif5b	kinesin family member 5B	18 1.0 cM	U86090
110454	Ly6a	lymphocyte antigen 6 complex, locus A	15 D3\|15 42.7 cM	X04653
17025	Alad	aminolevulinate, delta-, dehydratase	4 B3\|4 30.6 cM	X13752
19659	Rbp1	retinol binding protein 1, cellular	9 E3.3\|9 52.0 cM	X60367
14806	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	10 B3\|10 27.0 cM	X66117
19941	Rpl26	ribosomal protein L26	11 B3	X80699
11815	Apod	apolipoprotein D	16 B2\|16 21.2 cM	X82648
11482	Acvrl1	activin A receptor, type II-like 1	15 F3	Z31664
				AA420337
12716	Ckmt1	creatine kinase, mitochondrial 1, ubiquitous	2 F1-F3\|2 67.6 cM	AV091448
17217	Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	16 B1\|16 9.2 cM	D26089
67231	Tbc1d20	TBC1 domain family, member 20	2 H1	AW121234
242785	Klhl21	kelch-like 21 (Drosophila)	4 E2	AI882440
				AI847033