ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tbc1d20

Full Name:

TBC1 domain family, member 20

Alias:

1110028I04Rik|2810442O16Rik|AI414693

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 H1

Physical Location:

152119607-152138325 on NC_000068.6

Gene Type:

protein-coding

Human Ortholog:

GeneID: 128637 Symbol (Name): TBC1D20 (TBC1 domain family, member 20)

Ortholog Status:

The human GeneID 128637 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AW121234
Note:		Differences expression between alcohol treatment and control groups

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_024196.3	NP_077158.1	NC_000068.6 range: 152119607..152138325

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005096	GTPase activator activity	Molecular Function	IEA
GO:0005097	Rab GTPase activator activity	Molecular Function	IEA
GO:0032313	regulation of Rab GTPase activity	Biological Process	IEA