ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Kif5b

Full Name:

kinesin family member 5B

Alias:

AL022807|KHC

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

18 1.0 cM

Physical Location:

6202208-6241497 on NC_000084.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3799 Symbol (Name): KIF5B (kinesin family member 5B)

Ortholog Status:

The human GeneID 3799 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		U86090
Note:		Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains

Dataset Information

Name:		15282116
Method:		Microarray
Tissue:		Striata
Phenotype:		Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:		Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:		Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008448.2	NP_032474.2	NC_000084.5 range: 6202208..6241497, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043227	membrane-bounded organelle	Cellular Component	IDA (12805290)
GO:0043005	neuron projection	Cellular Component	IDA (16301330)
GO:0035253	ciliary rootlet	Cellular Component	IDA (16018997)
GO:0005875	microtubule associated complex	Cellular Component	IEA
GO:0005874	microtubule	Cellular Component	IEA
GO:0005871	kinesin complex	Cellular Component	TAS (10964943)
GO:0005737	cytoplasm	Cellular Component	IDA (16018997)
GO:0003774	motor activity	Molecular Function	IEA
GO:0003777	microtubule motor activity	Molecular Function	TAS (10964943)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (9624122)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0007017	microtubule-based process	Biological Process	TAS (11486041)
GO:0006839	mitochondrial transport	Biological Process	TAS (11486041)
GO:0007028	cytoplasm organization and biogenesis	Biological Process	IMP (9657148)
GO:0007018	microtubule-based movement	Biological Process	IEA