Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:14296
Full Name:frequently rearranged in advanced T-cell lymphomas
Organism:Mus musculus (Mouse)
Genetic Location:19 C3|19 37.5 cM
Physical Location:41904605-41907072 on NC_000085.5
Gene Type:protein-coding
Human Ortholog:GeneID: 10023    Symbol (Name): FRAT1 (frequently rearranged in advanced T-cell lymphomas)
Ortholog Status:The human GeneID 10023 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:U58974
Note:Differences expression in alcohol-preferring and alcohol-nonpreferring mouse strains
Dataset Information
Phenotype:Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration
Publication:Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed
Summary:Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Calw2/Alcdp2Chronic Alcohol Withdrawal194736.5-ter (cM)5.36.00E-07SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_008043.2NP_032069.2NC_000085.5 range: 41904605..41907072
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0000578embryonic axis specificationBiological ProcessIDA (10534617)
GO:0016055Wnt receptor signaling pathwayBiological ProcessIGI (15681612)
Other Database Cross Links
NCBI Entrez Gene:14296