ERGR - Ethanol-Related Gene Resource

Dataset Description

Dataset Name: 15282116

Species: Mouse

No. of Genes: 56

Tissue: Striata

Phenotype: Alcohol-nonpreferring, alcohol-preferring, alcohol self-administration

Publication: Saito et al. Alcohol. (2004) Mouse striatal transcriptome analysis: effects of oral self-administration of alcohol. PubMed

Dataset Summary: Aiming to define pathways among genomic, neural, and behavioral determinants of addiction, we investigated global striatal gene expression in a paradigm of oral self-administration of alcohol by using genomically very similar alcohol-nonpreferring B6.Cb(5)i(7)-alpha 3/Vad (C5A3) and alcohol-preferring B6.Ib(5)i(7)-beta 25A/Vad (I5B25A) quasi-congenic mouse strains and their progenitors, C57BL/6By (B6By) and BALB/cJ. Expression of 12,488 genes and expressed sequence tags (ESTs) was studied by using 24 high-density oligonucleotide microarrays. As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.

Gene list of this dataset (56 genes)

GeneID Symbol Name Genetic location Original ID1 Original ID2
14412 Slc6a13 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 6 F1 AA673769
77090 Ocel1 occludin/ELL domain containing 1 8 C1 AA689927
114896 Afg3l1 AFG3(ATPase family gene 3)-like 1 (yeast) 8 E1-E2 AA797556
73824 Snhg6 small nucleolar RNA host gene (non-protein coding) 6 - AA874329
19174 Psmb5-ps proteasome (prosome, macropain) subunit, beta type 5, pseudogene 11 E1|11 60.0 cM AB003305
12371 Casp9 caspase 9 4 E1 AB019600
54526 Syt10 synaptotagmin X 15 F1 AB026807
12804 Cntfr ciliary neurotrophic factor receptor 4 A5|4 19.9 cM AF068615
12704 Cit citron 5 F AF086824
53625 B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 11 A3.2|11 12.0 cM AF092050
6293 AF100956
AI153421
94184 Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 16 A1 AI180784
66687 Tbc1d15 TBC1 domain family, member 15 10 D2 AI194333
78785 Clip4 CAP-GLY domain containing linker protein family, member 4 17 E2 AI504338
232879 Zbtb45 zinc finger and BTB domain containing 45 7 A1 AI595382
110695 Aldh7a1 aldehyde dehydrogenase family 7, member A1 18 D3|18 29.0 cM AI835461
68183 Bcas2 breast carcinoma amplified sequence 2 3 F2.2 AI838996
113868 Acaa1a acetyl-Coenzyme A acyltransferase 1A 9 F4|9 71.0 cM AI841705
94184 Pdxdc1 pyridoxal-dependent decarboxylase domain containing 1 16 A1 AI843518
66776 4933439C20Rik RIKEN cDNA 4933439C20 gene - AI845165
109229 Ppp4r1l protein phosphatase 4, regulatory subunit 1-like 9 A5.3 AI847282
233802 Thumpd1 THUMP domain containing 1 7 F2|7 59.0 cM AI851052
16413 Itgb1bp1 integrin beta 1 binding protein 1 12 A1.2 AJ001373
23955 Nek4 NIMA (never in mitosis gene a)-related expressed kinase 4 14 B AJ223071
AV292380
AV339278
AV354117
71853 Pdia6 protein disulfide isomerase associated 6 12 A1.1 AW045202
239691 AU021092 expressed sequence AU021092 16 A1 AW045808
66184 Rps4y2 ribosomal protein S4, Y-linked 2 6 G3 AW046496
68845 Pih1d1 PIH1 domain containing 1 7 B4 AW048608
17434 Mocs2 molybdenum cofactor synthesis 2 13 D2.2 AW060325
68936 1190017O12Rik RIKEN cDNA 1190017O12 gene 16 C4 AW122061
68644 Abhd14a abhydrolase domain containing 14A 9 F1 AW123271
59090 Midn midnolin 10 C1 AW124785
AW214336
50706 Postn periostin, osteoblast specific factor 3 C D13664
12890 Cplx2 complexin 2 13 B1 D38613
17476 Mpeg1 macrophage expressed gene 1 19 A L20315
12039 Bckdha branched chain ketoacid dehydrogenase E1, alpha polypeptide - L47335
11482 Acvrl1 activin A receptor, type II-like 1 15 F3 L48015
17527 Mpv17 Mpv17 transgene, kidney disease mutant 5 B1 M36411
M55424
11668 Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 19 B|19 12.0 cM M74570
13036 Ctsh cathepsin H 9 E3.1|9 50.0 cM U06119
16524 Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 1 H3|1 94.2 cM U11860
14688 Gnb1 guanine nucleotide binding protein (G protein), beta 1 4 E2|4 79.4 cM U29055
22608 Ybx1 Y box protein 1 4 D1 U33196
22630 Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 12 A1.3 U56243
14296 Frat1 frequently rearranged in advanced T-cell lymphomas 19 C3|19 37.5 cM U58974
16573 Kif5b kinesin family member 5B 18 1.0 cM U86090
110454 Ly6a lymphocyte antigen 6 complex, locus A 15 D3|15 42.7 cM X04653
17025 Alad aminolevulinate, delta-, dehydratase 4 B3|4 30.6 cM X13752
19659 Rbp1 retinol binding protein 1, cellular 9 E3.3|9 52.0 cM X60367
14806 Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 10 B3|10 27.0 cM X66117
19941 Rpl26 ribosomal protein L26 11 B3 X80699
11815 Apod apolipoprotein D 16 B2|16 21.2 cM X82648
11482 Acvrl1 activin A receptor, type II-like 1 15 F3 Z31664
AA420337
12716 Ckmt1 creatine kinase, mitochondrial 1, ubiquitous 2 F1-F3|2 67.6 cM AV091448
17217 Mcm4 minichromosome maintenance deficient 4 homolog (S. cerevisiae) 16 B1|16 9.2 cM D26089
67231 Tbc1d20 TBC1 domain family, member 20 2 H1 AW121234
242785 Klhl21 kelch-like 21 (Drosophila) 4 E2 AI882440
AI847033

GeneID	Symbol	Name	Genetic location	Original ID1	Original ID2
14412	Slc6a13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	6 F1	AA673769
77090	Ocel1	occludin/ELL domain containing 1	8 C1	AA689927
114896	Afg3l1	AFG3(ATPase family gene 3)-like 1 (yeast)	8 E1-E2	AA797556
73824	Snhg6	small nucleolar RNA host gene (non-protein coding) 6	-	AA874329
19174	Psmb5-ps	proteasome (prosome, macropain) subunit, beta type 5, pseudogene	11 E1\|11 60.0 cM	AB003305
12371	Casp9	caspase 9	4 E1	AB019600
54526	Syt10	synaptotagmin X	15 F1	AB026807
12804	Cntfr	ciliary neurotrophic factor receptor	4 A5\|4 19.9 cM	AF068615
12704	Cit	citron	5 F	AF086824
53625	B3gnt2	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	11 A3.2\|11 12.0 cM	AF092050
6293				AF100956
				AI153421
94184	Pdxdc1	pyridoxal-dependent decarboxylase domain containing 1	16 A1	AI180784
66687	Tbc1d15	TBC1 domain family, member 15	10 D2	AI194333
78785	Clip4	CAP-GLY domain containing linker protein family, member 4	17 E2	AI504338
232879	Zbtb45	zinc finger and BTB domain containing 45	7 A1	AI595382
110695	Aldh7a1	aldehyde dehydrogenase family 7, member A1	18 D3\|18 29.0 cM	AI835461
68183	Bcas2	breast carcinoma amplified sequence 2	3 F2.2	AI838996
113868	Acaa1a	acetyl-Coenzyme A acyltransferase 1A	9 F4\|9 71.0 cM	AI841705
94184	Pdxdc1	pyridoxal-dependent decarboxylase domain containing 1	16 A1	AI843518
66776	4933439C20Rik	RIKEN cDNA 4933439C20 gene	-	AI845165
109229	Ppp4r1l	protein phosphatase 4, regulatory subunit 1-like	9 A5.3	AI847282
233802	Thumpd1	THUMP domain containing 1	7 F2\|7 59.0 cM	AI851052
16413	Itgb1bp1	integrin beta 1 binding protein 1	12 A1.2	AJ001373
23955	Nek4	NIMA (never in mitosis gene a)-related expressed kinase 4	14 B	AJ223071
				AV292380
				AV339278
				AV354117
71853	Pdia6	protein disulfide isomerase associated 6	12 A1.1	AW045202
239691	AU021092	expressed sequence AU021092	16 A1	AW045808
66184	Rps4y2	ribosomal protein S4, Y-linked 2	6 G3	AW046496
68845	Pih1d1	PIH1 domain containing 1	7 B4	AW048608
17434	Mocs2	molybdenum cofactor synthesis 2	13 D2.2	AW060325
68936	1190017O12Rik	RIKEN cDNA 1190017O12 gene	16 C4	AW122061
68644	Abhd14a	abhydrolase domain containing 14A	9 F1	AW123271
59090	Midn	midnolin	10 C1	AW124785
				AW214336
50706	Postn	periostin, osteoblast specific factor	3 C	D13664
12890	Cplx2	complexin 2	13 B1	D38613
17476	Mpeg1	macrophage expressed gene 1	19 A	L20315
12039	Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	-	L47335
11482	Acvrl1	activin A receptor, type II-like 1	15 F3	L48015
17527	Mpv17	Mpv17 transgene, kidney disease mutant	5 B1	M36411
				M55424
11668	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	19 B\|19 12.0 cM	M74570
13036	Ctsh	cathepsin H	9 E3.1\|9 50.0 cM	U06119
16524	Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	1 H3\|1 94.2 cM	U11860
14688	Gnb1	guanine nucleotide binding protein (G protein), beta 1	4 E2\|4 79.4 cM	U29055
22608	Ybx1	Y box protein 1	4 D1	U33196
22630	Ywhaq	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	12 A1.3	U56243
14296	Frat1	frequently rearranged in advanced T-cell lymphomas	19 C3\|19 37.5 cM	U58974
16573	Kif5b	kinesin family member 5B	18 1.0 cM	U86090
110454	Ly6a	lymphocyte antigen 6 complex, locus A	15 D3\|15 42.7 cM	X04653
17025	Alad	aminolevulinate, delta-, dehydratase	4 B3\|4 30.6 cM	X13752
19659	Rbp1	retinol binding protein 1, cellular	9 E3.3\|9 52.0 cM	X60367
14806	Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	10 B3\|10 27.0 cM	X66117
19941	Rpl26	ribosomal protein L26	11 B3	X80699
11815	Apod	apolipoprotein D	16 B2\|16 21.2 cM	X82648
11482	Acvrl1	activin A receptor, type II-like 1	15 F3	Z31664
				AA420337
12716	Ckmt1	creatine kinase, mitochondrial 1, ubiquitous	2 F1-F3\|2 67.6 cM	AV091448
17217	Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	16 B1\|16 9.2 cM	D26089
67231	Tbc1d20	TBC1 domain family, member 20	2 H1	AW121234
242785	Klhl21	kelch-like 21 (Drosophila)	4 E2	AI882440
				AI847033