ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cyp17a1

Full Name:

cytochrome P450, family 17, subfamily a, polypeptide 1

Alias:

Cyp17|p450c17

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 C3|19 46.0 cM

Physical Location:

46741669-46747463 on NC_000085.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1586 Symbol (Name): CYP17A1 (cytochrome P450, family 17, subfamily A, polypeptide 1)

Ortholog Status:

The human GeneID 1586 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007809.3	NP_031835.3	NC_000085.5 range: 46741669..46747463, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043025	cell soma	Cellular Component	IDA (7588260)
GO:0030424	axon	Cellular Component	IDA (7588260)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0016020	membrane	Cellular Component	IEA
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0016829	lyase activity	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0004508	steroid 17-alpha-monooxygenase activity	Molecular Function	IMP (15169901)
GO:0004508	steroid 17-alpha-monooxygenase activity	Molecular Function	IDA (7588219)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006704	glucocorticoid biosynthetic process	Biological Process	IDA (7588219)
GO:0006700	C21-steroid hormone biosynthetic process	Biological Process	IEA