ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CYP17A1

Full Name:

cytochrome P450, family 17, subfamily A, polypeptide 1

Alias:

CPT7|CYP17|P450C17|S17AH

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

10q24.3

Physical Location:

104580277-104587279 on NC_000010.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 13074 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CYP17A1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000102.3	NP_000093.1	NC_000010.9 range: 104580277..104587279, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	NAS (9326943)
GO:0005789	endoplasmic reticulum membrane	Cellular Component	EXP (10406467)
GO:0005792	microsome	Cellular Component	NR
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0019825	oxygen binding	Molecular Function	TAS (2808364)
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0004508	steroid 17-alpha-monooxygenase activity	Molecular Function	TAS (1347802)
GO:0004508	steroid 17-alpha-monooxygenase activity	Molecular Function	EXP (10406467)
GO:0007548	sex differentiation	Biological Process	TAS (9326943)
GO:0006700	C21-steroid hormone biosynthetic process	Biological Process	IEA