ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cyp8b1

Full Name:

cytochrome P450, family 8, subfamily b, polypeptide 1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 F4|9 71.0 cM

Physical Location:

121823473-121825408 on NC_000075.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1582 Symbol (Name): CYP8B1 (cytochrome P450, family 8, subfamily B, polypeptide 1)

Ortholog Status:

The human GeneID 1582 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact2	Alcohol Stimulated Activity	9	61	51-71 (cM)	3.6	4.30E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010012.2	NP_034142.2	NC_000075.5 range: 121823473..121825408, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0005792	microsome	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0033778	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	Molecular Function	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA