ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CYP8B1

Full Name:

cytochrome P450, family 8, subfamily B, polypeptide 1

Alias:

CP8B|CYP12|FLJ17826

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3p22-p21.3

Physical Location:

42888687-42892636 on NC_000003.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 13124 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CYP8B1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004391.2	NP_004382.2	NC_000003.10 range: 42888687..42892636, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005792	microsome	Cellular Component	IEA
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IEA
GO:0005789	endoplasmic reticulum membrane	Cellular Component	EXP (10051404)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0020037	heme binding	Molecular Function	IEA
GO:0019825	oxygen binding	Molecular Function	TAS (10051404)
GO:0033778	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	Molecular Function	IEA
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0008397	sterol 12-alpha-hydroxylase activity	Molecular Function	TAS (10051404)
GO:0008397	sterol 12-alpha-hydroxylase activity	Molecular Function	EXP (10051404)
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA