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Gene Information
Gene ID:13669
Symbol:Eif3s10
Full Name:eukaryotic translation initiation factor 3, subunit 10 (theta)
Alias:A830012B05Rik|Csma|Eif3|mKIAA0139
Organism:Mus musculus (Mouse)
Chromosome:19
Genetic Location:19 D
Physical Location:60837024-60866545 on NC_000085.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 8661    Symbol (Name): EIF3A (eukaryotic translation initiation factor 3, subunit A)
Ortholog Status:The human GeneID 8661 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1448425 (probe)
Original ID2:Eif3s10
Fold Change:1.28
P Value:5.30E-06
Note:Highest priority differential expression on 430A array. Direction: B6>D2; Cis LOD:3.3
Dataset Information
Name:15597075
Method:Microarray and QTL
Tissue:Brain
Phenotype:Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_010123.3NP_034253.3NC_000085.5 range: 60837024..60866545, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0003743translation initiation factor activityMolecular FunctionIEA
GO:0006412translationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:13669
MGI:
Ensembl:ENSMUSG00000024991
dbSNP:Eif3s10
AceView:Eif3s10