ERGR - Ethanol-Related Gene Resource

Dataset Description

Dataset Name: 15597075

Species: Mouse

No. of Genes: 58

Tissue: Brain

Phenotype: Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity

Publication: Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed

Dataset Summary: Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.

Gene list of this dataset (58 genes)
Page: 1 2 list all
GeneID Symbol Name Genetic location Original ID1 Original ID2
15939 Ier5 immediate early response 5 1 G3|1 81.5 cM 1460009 (probe) Ier5
14455 Gas5 growth arrest specific 5 1 H2.1 1449410 (probe) Gas5
17926 Myoc myocilin 1 H2.1|1 83.6 cM 1450468 (probe) Myoc
16579 Kifap3 kinesin-associated protein 3 1 H1 1451783 (probe) Kifap3
1419716 (probe) Pou2fl
66447 Mgst3 microsomal glutathione S-transferase 3 1 H2 1448300 (probe) Mgst3
56009 Refbp2 RNA and export factor binding protein 2 1 H3 1422993 (probe) Refbp2
12847 Copa coatomer protein complex subunit alpha 1 H3|1 93.5 cM 1415706 (probe) Copa
1434893 (probe) EST
1455136 (probe) EST
16524 Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 1 H3|1 94.2 cM 1426115 (probe) Kcnj9
1419601 (probe) Kenj10
13349 Darc Duffy blood group, chemokine receptor 1 H3|1 94.0 cM 1432273 (probe) Dfy
226695 Ifi205 interferon activated gene 205 1 H3|1 95.3 cM 1426906 (probe) Ifi205
54418 Fmn2 formin 2 1 H3|1 96.0 cM 1431725 (probe) Fmn2
1423871 (probe) EST
1453018 (probe) cDNA
1429763 (probe) cDNA
12509 Cd59a CD59a antigen 2 55.0 cM 1429830 (probe) Cd59a
20394 Scg5 secretogranin V 2 E5|2 64.0 cM 1423150 (probe) Sgne1
1425343 (probe) cDNA
17025 Alad aminolevulinate, delta-, dehydratase 4 B3|4 30.6 cM 1424877 (probe) Alad
17475 Mpdz multiple PDZ domain protein 4 C3|4 38.6 cM 1418664 (probe) Mpdz
1428760 (probe) cDNA
20104 Rps6 ribosomal protein S6 4 C3 1416142 (probe) Rps6
230379 Asah3l N-acylsphingosine amidohydrolase 3-like 4 C4 1451355 (probe) CRG-L1
1450967 (probe) cDNA
1448250 (probe) cDNA
20660 Sorl1 sortilin-related receptor, LDLR class A repeats-containing - 1426258 (probe) Sorl1
235293 Sc5d sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) 9 B 1451457 (probe) Sc5d
17967 Ncam1 neural cell adhesion molecule 1 9 A5.3|9 28.0 cM 1426865 (probe) Ncam1
12955 Cryab crystallin, alpha B 9 A5.3|9 29.0 cM 1416455 (probe) Cryab
1417211 (probe) cDNA
1448845 (probe) EST
22003 Tpm1 tropomyosin 1, alpha 9 C|9 40.0 cM 1423049 (probe) Tpm1
59046 Arpp19 cAMP-regulated phosphoprotein 19 9 E1 1450685 (probe) Arpp19
70769 Nolc1 nucleolar and coiled-body phosphoprotein 1 19 C3 1428870 (probe) Nolc1
13669 Eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) 19 D 1448425 (probe) Eif3s10
94281 Sfxn4 sideroflexin 4 19 D3 1418873 (probe) Sfxn4
1455072 (probe) cDNA
26374 Rfwd2 ring finger and WD repeat domain 2 1 C3 1426912 (probe) Cop1
64659 Mrps14 mitochondrial ribosomal protein S14 1 H2.1 1420489 (probe) Mrps14
56752 Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 1 H2 1437388 (probe) Aldh9a1
1448630 (probe) Sdhe
1429382 (probe) EST
226646 Ndufs2 NADH dehydrogenase (ubiquinone) Fe-S protein 2 1 H3 1451096 (probe) Ndufs2
1421096 (probe) Pdfn2
98193 Wdr42a WD repeat domain 42A 1 H3 1434133 (probe) D1Ucla4
98660 Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1 H3|1 94.2 cM 1427465 (probe) Atp1a2
94332 Cadm3 cell adhesion molecule 3 1 H3 1418921 (probe) Necl1
Page: 1 2 list all

GeneID	Symbol	Name	Genetic location	Original ID1	Original ID2
15939	Ier5	immediate early response 5	1 G3\|1 81.5 cM	1460009 (probe)	Ier5
14455	Gas5	growth arrest specific 5	1 H2.1	1449410 (probe)	Gas5
17926	Myoc	myocilin	1 H2.1\|1 83.6 cM	1450468 (probe)	Myoc
16579	Kifap3	kinesin-associated protein 3	1 H1	1451783 (probe)	Kifap3
				1419716 (probe)	Pou2fl
66447	Mgst3	microsomal glutathione S-transferase 3	1 H2	1448300 (probe)	Mgst3
56009	Refbp2	RNA and export factor binding protein 2	1 H3	1422993 (probe)	Refbp2
12847	Copa	coatomer protein complex subunit alpha	1 H3\|1 93.5 cM	1415706 (probe)	Copa
				1434893 (probe)	EST
				1455136 (probe)	EST
16524	Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	1 H3\|1 94.2 cM	1426115 (probe)	Kcnj9
				1419601 (probe)	Kenj10
13349	Darc	Duffy blood group, chemokine receptor	1 H3\|1 94.0 cM	1432273 (probe)	Dfy
226695	Ifi205	interferon activated gene 205	1 H3\|1 95.3 cM	1426906 (probe)	Ifi205
54418	Fmn2	formin 2	1 H3\|1 96.0 cM	1431725 (probe)	Fmn2
				1423871 (probe)	EST
				1453018 (probe)	cDNA
				1429763 (probe)	cDNA
12509	Cd59a	CD59a antigen	2 55.0 cM	1429830 (probe)	Cd59a
20394	Scg5	secretogranin V	2 E5\|2 64.0 cM	1423150 (probe)	Sgne1
				1425343 (probe)	cDNA
17025	Alad	aminolevulinate, delta-, dehydratase	4 B3\|4 30.6 cM	1424877 (probe)	Alad
17475	Mpdz	multiple PDZ domain protein	4 C3\|4 38.6 cM	1418664 (probe)	Mpdz
				1428760 (probe)	cDNA
20104	Rps6	ribosomal protein S6	4 C3	1416142 (probe)	Rps6
230379	Asah3l	N-acylsphingosine amidohydrolase 3-like	4 C4	1451355 (probe)	CRG-L1
				1450967 (probe)	cDNA
				1448250 (probe)	cDNA
20660	Sorl1	sortilin-related receptor, LDLR class A repeats-containing	-	1426258 (probe)	Sorl1
235293	Sc5d	sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)	9 B	1451457 (probe)	Sc5d
17967	Ncam1	neural cell adhesion molecule 1	9 A5.3\|9 28.0 cM	1426865 (probe)	Ncam1
12955	Cryab	crystallin, alpha B	9 A5.3\|9 29.0 cM	1416455 (probe)	Cryab
				1417211 (probe)	cDNA
				1448845 (probe)	EST
22003	Tpm1	tropomyosin 1, alpha	9 C\|9 40.0 cM	1423049 (probe)	Tpm1
59046	Arpp19	cAMP-regulated phosphoprotein 19	9 E1	1450685 (probe)	Arpp19
70769	Nolc1	nucleolar and coiled-body phosphoprotein 1	19 C3	1428870 (probe)	Nolc1
13669	Eif3s10	eukaryotic translation initiation factor 3, subunit 10 (theta)	19 D	1448425 (probe)	Eif3s10
94281	Sfxn4	sideroflexin 4	19 D3	1418873 (probe)	Sfxn4
				1455072 (probe)	cDNA
26374	Rfwd2	ring finger and WD repeat domain 2	1 C3	1426912 (probe)	Cop1
64659	Mrps14	mitochondrial ribosomal protein S14	1 H2.1	1420489 (probe)	Mrps14
56752	Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	1 H2	1437388 (probe)	Aldh9a1
				1448630 (probe)	Sdhe
				1429382 (probe)	EST
226646	Ndufs2	NADH dehydrogenase (ubiquinone) Fe-S protein 2	1 H3	1451096 (probe)	Ndufs2
				1421096 (probe)	Pdfn2
98193	Wdr42a	WD repeat domain 42A	1 H3	1434133 (probe)	D1Ucla4
98660	Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	1 H3\|1 94.2 cM	1427465 (probe)	Atp1a2
94332	Cadm3	cell adhesion molecule 3	1 H3	1418921 (probe)	Necl1