ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mrps14

Full Name:

mitochondrial ribosomal protein S14

Alias:

1810032L21Rik|AL022847|Rpms14

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H2.1

Physical Location:

162125390-162131316 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 63931 Symbol (Name): MRPS14 (mitochondrial ribosomal protein S14)

Ortholog Status:

The human GeneID 63931 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		1420489 (probe)
Original ID2:		Mrps14
Fold Change:		1.27
P Value:		4.50E-05
Note:		Moderate priority differential expression on 430A array. Direction: D2>B6; Cis LOD:8.2

Dataset Information

Name:		15597075
Method:		Microarray and QTL
Tissue:		Brain
Phenotype:		Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:		Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:		Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_025474.3	NP_079750.1	NC_000067.5 range: 162125390..162131316

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0005622	intracellular	Cellular Component	RCA (12466851)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0005763	mitochondrial small ribosomal subunit	Cellular Component	ISS (10938081)
GO:0005840	ribosome	Cellular Component	RCA (12466851)
GO:0030529	ribonucleoprotein complex	Cellular Component	IEA
GO:0003735	structural constituent of ribosome	Molecular Function	ISS (10938081)
GO:0006412	translation	Biological Process	RCA (12466851)