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Gene Information
Gene ID:230379
Symbol:Asah3l
Full Name:N-acylsphingosine amidohydrolase 3-like
Alias:2410116I05Rik|Acer2|CRG-L1|maCER2
Organism:Mus musculus (Mouse)
Chromosome:4
Genetic Location:4 C4
Physical Location:86520367-86566778 on NC_000070.5
Gene Type:protein-coding
Human Ortholog:GeneID: 340485    Symbol (Name): ASAH3L (N-acylsphingosine amidohydrolase 3-like)
Ortholog Status:The human GeneID 340485 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1451355 (probe)
Original ID2:CRG-L1
Fold Change:1.27
P Value:2.20E-07
Note:Highest priority differential expression on 430A array. Direction: D2>B6; Cis LOD:7.4
Dataset Information
Name:15597075
Method:Microarray and QTL
Tissue:Brain
Phenotype:Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_139306.1NP_647467.1NC_000070.5 range: 86520367..86566778
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000139Golgi membraneCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIEA
GO:0005794Golgi apparatusCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0016787hydrolase activityMolecular FunctionIEA
GO:0016811hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidesMolecular FunctionIEA
GO:0006629lipid metabolic processBiological ProcessIEA
GO:0006672ceramide metabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:230379
MGI:
Ensembl:ENSMUSG00000038007
dbSNP:Asah3l
AceView:Asah3l