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Gene Information
Gene ID:94281
Symbol:Sfxn4
Full Name:sideroflexin 4
Alias:MGC107253
Organism:Mus musculus (Mouse)
Chromosome:19
Genetic Location:19 D3
Physical Location:60914663-60937314 on NC_000085.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 119559    Symbol (Name): SFXN4 (sideroflexin 4)
Ortholog Status:The human GeneID 119559 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1418873 (probe)
Original ID2:Sfxn4
Fold Change:1.27
P Value:5.00E-07
Note:Highest priority differential expression on 430A array. Direction: D2>B6; Cis LOD:10.3
Dataset Information
Name:15597075
Method:Microarray and QTL
Tissue:Brain
Phenotype:Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_053198.2NP_444428.2NC_000085.5 range: 60914663..60937314, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentRCA (12466851)
GO:0005739mitochondrionCellular ComponentIDA (14651853)
GO:0005739mitochondrionCellular ComponentISS (11274051)
GO:0016020membraneCellular ComponentRCA (12466851)
GO:0008324cation transmembrane transporter activityMolecular FunctionRCA (12466851)
GO:0005506iron ion bindingMolecular FunctionIEA
GO:0006826iron ion transportBiological ProcessIEA
GO:0006811ion transportBiological ProcessIEA
GO:0006810transportBiological ProcessIEA
GO:0006812cation transportBiological ProcessRCA (12466851)
Other Database Cross Links
NCBI Entrez Gene:94281
MGI:
Ensembl:ENSMUSG00000063698
dbSNP:Sfxn4
AceView:Sfxn4