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Gene Information
Gene ID:226695
Symbol:Ifi205
Full Name:interferon activated gene 205
Alias:D3|D3cDNA
Organism:Mus musculus (Mouse)
Chromosome:1
Genetic Location:1 H3|1 95.3 cM
Physical Location:175942128-175961885 on NC_000067.5, complement
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1426906 (probe)
Original ID2:Ifi205
Fold Change:1.18
P Value:1.20E-05
Note:Highest priority differential expression on 430A array. Direction: B6>D2; Cis LOD:8.4
Dataset Information
Name:15597075
Method:Microarray and QTL
Tissue:Brain
Phenotype:Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcw1Acute Alcohol Withdrawal196172.3-176.5 (Mb)5.63.00E-07SignificantPARC
Calw1/Alcdp1Chronic Alcohol Withdrawal19689-106.3 (cM)7.62.00E-09SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_172648.3NP_766236.2NC_000067.5 range: 175942128..175961885, complement
Other Database Cross Links
NCBI Entrez Gene:226695
MGI:
Ensembl:ENSMUSG00000054203
dbSNP:Ifi205
AceView:Ifi205