ERGR - Ethanol-Related Gene Resource

Dataset Description

Dataset Name: 15597075

Species: Mouse

No. of Genes: 58

Tissue: Brain

Phenotype: Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity

Publication: Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed

Dataset Summary: Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.

Gene list of this dataset (58 genes)
Page: 1 2 list all
GeneID Symbol Name Genetic location Original ID1 Original ID2
15950 Ifi203 interferon activated gene 203 1 H3|1 95.31 cM 1448775 (probe) Ifi203
13849 Ephx1 epoxide hydrolase 1, microsomal 1 H4|1 98.5 cM 1422438 (probe) Ephx1
17684 Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 10 A2 1417129 (probe) Mrg1
56357 Ivd isovaleryl coenzyme A dehydrogenase - 1418238 (probe) Ivd
1428196 (probe) cDNA
228550 Itpka inositol 1,4,5-trisphosphate 3-kinase A 2 E5 1424037 (probe) Itpka
1451469 (probe) cDNA
1427570 (probe) cDNA
1427437 (probe) 1427437
84004 Mcam melanoma cell adhesion molecule 9 A5.1 1416357 (probe) Mcam
12282 Hyou1 hypoxia up-regulated 1 9 B 1423290 (probe) Cab140
1424468 (probe) cDNA
1417474 (probe) cDNA
14148 Fdx1 ferredoxin 1 9 B 1449108 (probe) Fdx1
24044 Scamp2 secretory carrier membrane protein 2 9 B 1448404 (probe) Scamp2
22003 Tpm1 tropomyosin 1, alpha 9 C|9 40.0 cM 1423721 (probe) Tpm1
1426556 (probe) cDNA
50772 Mapk6 mitogen-activated protein kinase 6 9 D|9 38.0 cM 1419169 (probe) Mapk6
20249 Scd1 stearoyl-Coenzyme A desaturase 1 19 C3|19 43.0 cM 1415964 (probe) Scd1
1449202 (probe) Scma4g
1425680 (probe) Btre
57344 As3mt arsenic (+3 oxidation state) methyltransferase 19 D1 1431980 (probe) Cyt19
226180 Ina internexin neuronal intermediate filament protein, alpha 19 C3 1448991 (probe) Ina
226180 Ina internexin neuronal intermediate filament protein, alpha 19 C3 1418178 (probe) Ina
14873 Gsto1 glutathione S-transferase omega 1 19 D1 1456036 (probe) Gsto1
1425111 (probe) cDNA
170750 Xpnpep1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 19 D2 1422443 (probe) Xpnpep1
1434162 (probe) cDNA
11757 Prdx3 peroxiredoxin 3 19 D3|19 50.0 cM 1416292 (probe) Prdx3
17926 Myoc myocilin 1 H2.1|1 83.6 cM 94122 (probe) Myoc
18986 Pou2f1 POU domain, class 2, transcription factor 1 1 H2.3|1 87.2 cM 102894 (probe) Pou2f1
66447 Mgst3 microsomal glutathione S-transferase 3 1 H2 96258 (probe) Mgst3
56752 Aldh9a1 aldehyde dehydrogenase 9, subfamily A1 1 H2 96243 (probe) Aldh9a1
66052 Sdhc succinate dehydrogenase complex, subunit C, integral membrane protein 1 H3 94216 (probe) Sdhc
16524 Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 1 H3|1 94.2 cM 98332 (probe) Kcnj9
13349 Darc Duffy blood group, chemokine receptor 1 H3|1 94.0 cM 93412 (probe) Dfy
27058 Srp9 signal recognition particle 9 1 H5 101579 (probe) Srp9
12509 Cd59a CD59a antigen 2 55.0 cM 101516 (probe) Cd59a
20394 Scg5 secretogranin V 2 E5|2 64.0 cM 100131 (probe) Sgne1
17025 Alad aminolevulinate, delta-, dehydratase 4 B3|4 30.6 cM 101044 (probe) Alad
20660 Sorl1 sortilin-related receptor, LDLR class A repeats-containing - 100888 (probe) Sorl1
235293 Sc5d sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) 9 B 102769 (probe) Sc5d
27965 Spg21 spastic paraplegia 21 homolog (human) 9 C|9 40.0 cM 95430 (probe) D9Wsu18e
59046 Arpp19 cAMP-regulated phosphoprotein 19 9 E1 97260 (probe) Arpp19
16579 Kifap3 kinesin-associated protein 3 1 H1 100113 (probe) Kifap3
433375 Creg1 cellular repressor of E1A-stimulated genes 1 1 H2.3 160502 (probe) Creg
96854 (probe) EST
97254 (probe) Rbm8
97197 (probe) EST
19672 Rcn1 reticulocalbin 1 2 E3|2 58.0 cM 160896 (probe) Rcn
Page: 1 2 list all

GeneID	Symbol	Name	Genetic location	Original ID1	Original ID2
15950	Ifi203	interferon activated gene 203	1 H3\|1 95.31 cM	1448775 (probe)	Ifi203
13849	Ephx1	epoxide hydrolase 1, microsomal	1 H4\|1 98.5 cM	1422438 (probe)	Ephx1
17684	Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	10 A2	1417129 (probe)	Mrg1
56357	Ivd	isovaleryl coenzyme A dehydrogenase	-	1418238 (probe)	Ivd
				1428196 (probe)	cDNA
228550	Itpka	inositol 1,4,5-trisphosphate 3-kinase A	2 E5	1424037 (probe)	Itpka
				1451469 (probe)	cDNA
				1427570 (probe)	cDNA
				1427437 (probe)	1427437
84004	Mcam	melanoma cell adhesion molecule	9 A5.1	1416357 (probe)	Mcam
12282	Hyou1	hypoxia up-regulated 1	9 B	1423290 (probe)	Cab140
				1424468 (probe)	cDNA
				1417474 (probe)	cDNA
14148	Fdx1	ferredoxin 1	9 B	1449108 (probe)	Fdx1
24044	Scamp2	secretory carrier membrane protein 2	9 B	1448404 (probe)	Scamp2
22003	Tpm1	tropomyosin 1, alpha	9 C\|9 40.0 cM	1423721 (probe)	Tpm1
				1426556 (probe)	cDNA
50772	Mapk6	mitogen-activated protein kinase 6	9 D\|9 38.0 cM	1419169 (probe)	Mapk6
20249	Scd1	stearoyl-Coenzyme A desaturase 1	19 C3\|19 43.0 cM	1415964 (probe)	Scd1
				1449202 (probe)	Scma4g
				1425680 (probe)	Btre
57344	As3mt	arsenic (+3 oxidation state) methyltransferase	19 D1	1431980 (probe)	Cyt19
226180	Ina	internexin neuronal intermediate filament protein, alpha	19 C3	1448991 (probe)	Ina
226180	Ina	internexin neuronal intermediate filament protein, alpha	19 C3	1418178 (probe)	Ina
14873	Gsto1	glutathione S-transferase omega 1	19 D1	1456036 (probe)	Gsto1
				1425111 (probe)	cDNA
170750	Xpnpep1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	19 D2	1422443 (probe)	Xpnpep1
				1434162 (probe)	cDNA
11757	Prdx3	peroxiredoxin 3	19 D3\|19 50.0 cM	1416292 (probe)	Prdx3
17926	Myoc	myocilin	1 H2.1\|1 83.6 cM	94122 (probe)	Myoc
18986	Pou2f1	POU domain, class 2, transcription factor 1	1 H2.3\|1 87.2 cM	102894 (probe)	Pou2f1
66447	Mgst3	microsomal glutathione S-transferase 3	1 H2	96258 (probe)	Mgst3
56752	Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	1 H2	96243 (probe)	Aldh9a1
66052	Sdhc	succinate dehydrogenase complex, subunit C, integral membrane protein	1 H3	94216 (probe)	Sdhc
16524	Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	1 H3\|1 94.2 cM	98332 (probe)	Kcnj9
13349	Darc	Duffy blood group, chemokine receptor	1 H3\|1 94.0 cM	93412 (probe)	Dfy
27058	Srp9	signal recognition particle 9	1 H5	101579 (probe)	Srp9
12509	Cd59a	CD59a antigen	2 55.0 cM	101516 (probe)	Cd59a
20394	Scg5	secretogranin V	2 E5\|2 64.0 cM	100131 (probe)	Sgne1
17025	Alad	aminolevulinate, delta-, dehydratase	4 B3\|4 30.6 cM	101044 (probe)	Alad
20660	Sorl1	sortilin-related receptor, LDLR class A repeats-containing	-	100888 (probe)	Sorl1
235293	Sc5d	sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)	9 B	102769 (probe)	Sc5d
27965	Spg21	spastic paraplegia 21 homolog (human)	9 C\|9 40.0 cM	95430 (probe)	D9Wsu18e
59046	Arpp19	cAMP-regulated phosphoprotein 19	9 E1	97260 (probe)	Arpp19
16579	Kifap3	kinesin-associated protein 3	1 H1	100113 (probe)	Kifap3
433375	Creg1	cellular repressor of E1A-stimulated genes 1	1 H2.3	160502 (probe)	Creg
				96854 (probe)	EST
				97254 (probe)	Rbm8
				97197 (probe)	EST
19672	Rcn1	reticulocalbin 1	2 E3\|2 58.0 cM	160896 (probe)	Rcn