| Gene Information |
| Gene ID: | | 84004 |
| Symbol: | | Mcam |
| Full Name: | | melanoma cell adhesion molecule |
| Alias: | | 1-gicerin|AV025631|CD146|CD149|Muc18|s-endo|s-gicerin |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 9 |
| Genetic Location: | | 9 A5.1 |
| Physical Location: | | 43942753-43950806 on NC_000075.5 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 4162 Symbol (Name): MCAM (melanoma cell adhesion molecule) |
| Ortholog Status: | | The human GeneID 4162 is not in current human dataset. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | 1416357 (probe) | | Original ID2: | | Mcam | | Fold Change: | | 1.13 | | P Value: | | 2.30E-04 | | Note: | | Moderate priority differential expression on 430A array. Direction: B6>D2; Cis LOD:1 |
| | Dataset Information | | Name: | | 15597075 | | Method: | | Microarray and QTL | | Tissue: | | Brain | | Phenotype: | | Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity | | Publication: | | Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed | | Summary: | | Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005615 | extracellular space | Cellular Component | RCA (12466851) | |
| GO:0005886 | plasma membrane | Cellular Component | ISS (11255016) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0016021 | integral to membrane | Cellular Component | RCA (12466851) | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0007155 | cell adhesion | Biological Process | ISS (11255016) | |
| GO:0007157 | heterophilic cell adhesion | Biological Process | ISS (11255016) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 84004 |
| MGI: | |
| Ensembl: | | ENSMUSG00000032135 |
| dbSNP: | | Mcam |
| AceView: | | Mcam |
