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Gene Information
Gene ID:14148
Symbol:Fdx1
Full Name:ferredoxin 1
Organism:Mus musculus (Mouse)
Chromosome:9
Genetic Location:9 B
Physical Location:51751411-51771637 on NC_000075.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2230    Symbol (Name): FDX1 (ferredoxin 1)
Ortholog Status:The human GeneID 2230 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1449108 (probe)
Original ID2:Fdx1
Fold Change:1.19
P Value:2.10E-04
Note:Moderate priority differential expression on 430A array. Direction: D2>B6; Cis LOD:2.2
Dataset Information
Name:15597075
Method:Microarray and QTL
Tissue:Brain
Phenotype:Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_007996.1NP_032022.1NC_000075.5 range: 51751411..51771637, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentIDA (14651853)
GO:0005506iron ion bindingMolecular FunctionIEA
GO:0009055electron carrier activityMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0051536iron-sulfur cluster bindingMolecular FunctionIEA
GO:00515372 iron, 2 sulfur cluster bindingMolecular FunctionIEA
GO:0006810transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:14148
MGI:
Ensembl:ENSMUSG00000032051
dbSNP:Fdx1
AceView:Fdx1