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Gene Information
Gene ID:15950
Symbol:Ifi203
Full Name:interferon activated gene 203
Organism:Mus musculus (Mouse)
Chromosome:1
Genetic Location:1 H3|1 95.31 cM
Physical Location:175850530-175872622 on NC_000067.5, complement
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1448775 (probe)
Original ID2:Ifi203
Fold Change:1.13
P Value:3.50E-04
Note:Moderate priority differential expression on 430A array. Direction: B6>D2; Cis LOD:1.7
Dataset Information
Name:15597075
Method:Microarray and QTL
Tissue:Brain
Phenotype:Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcw1Acute Alcohol Withdrawal196172.3-176.5 (Mb)5.63.00E-07SignificantPARC
Calw1/Alcdp1Chronic Alcohol Withdrawal19689-106.3 (cM)7.62.00E-09SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001045481.1NP_001038946.1NC_000067.5 range: 175850530..175872622, complement
NM_008328.2NP_032354.2NC_000067.5 range: 175850530..175872622, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:15950
MGI:
Ensembl:ENSMUSG00000039997
dbSNP:Ifi203
AceView:Ifi203