ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Srp9

Full Name:

signal recognition particle 9

Alias:

9kDa

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H5

Physical Location:

184054880-184062518 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 6726 Symbol (Name): SRP9 (signal recognition particle 9kDa)

Ortholog Status:

The human GeneID 6726 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		101579 (probe)
Original ID2:		Srp9
Fold Change:		1.83
P Value:		1.60E-07
Note:		Highest priority differential expression on U74Av2 array. Direction: B6>D2; Cis LOD:6.9

Dataset Information

Name:		15597075
Method:		Microarray and QTL
Tissue:		Brain
Phenotype:		Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:		Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:		Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_012058.3	NP_036188.1	NC_000067.5 range: 184054880..184062518

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005786	signal recognition particle, endoplasmic reticulum targeting	Cellular Component	IEA
GO:0030529	ribonucleoprotein complex	Cellular Component	IEA
GO:0048500	signal recognition particle	Cellular Component	IEA
GO:0003723	RNA binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0008312	7S RNA binding	Molecular Function	IEA
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	Biological Process	IEA
GO:0045900	negative regulation of translational elongation	Biological Process	IEA