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Gene Information
Gene ID:70769
Full Name:nucleolar and coiled-body phosphoprotein 1
Organism:Mus musculus (Mouse)
Genetic Location:19 C3
Physical Location:46150352-46160019 on NC_000085.5
Gene Type:protein-coding
Human Ortholog:GeneID: 9221    Symbol (Name): NOLC1 (nucleolar and coiled-body phosphoprotein 1)
Ortholog Status:The human GeneID 9221 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:1428870 (probe)
Original ID2:Nolc1
Fold Change:1.17
P Value:4.00E-04
Note:Highest priority differential expression on 430A array. Direction: B6>D2; Cis LOD:3.9
Dataset Information
Method:Microarray and QTL
Phenotype:Acute ethanol withdrawal, Chronic ethanol withdrawal, Ethanol preference drinking, Ethanol-stimulated activity
Publication:Hitzemann et al. Alcohol Clin Exp Res. (2004) On the integration of alcohol-related quantitative trait loci and gene expression analyses. PubMed
Summary:Six ethanol-related QTLs, all detected in C57BL/6J and DBA/2J intercrosses were entered into the analysis.Brain gene expression data for the C57BL/6 and DBA/2 strains (n=6 per strain) and an F2 intercross sample (n=56) derived from these strains were obtained by using the Affymetrix U74Av2 and 430A arrays; additional data with the U74Av2 array were available for the extended amygdala, dorsomedial striatum, and hippocampus.Within the 6 QTL intervals, 39 transcripts (430A array) were identified as being highly likely to be differentially expressed between the C57BL/6 and DBA/2 strains at a false discovery rate of 0.01 or better. The p value is from the t test comparison between the C57BL/6J (B6) and DBA/2J (D2) inbred strains. The phenotype of each gene are based on the QTL phenotype.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001039351.1NP_001034440.1NC_000085.5 range: 46150352..46160019
NM_001039352.1NP_001034441.1NC_000085.5 range: 46150352..46160019
NM_001039353.1NP_001034442.1NC_000085.5 range: 46150352..46160019
NM_053086.2NP_444316.2NC_000085.5 range: 46150352..46160019
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005654nucleoplasmCellular ComponentIDA (11424213)
GO:0005730nucleolusCellular ComponentIDA (11470819)
GO:0015030Cajal bodyCellular ComponentIDA (11470819)
GO:0030532small nuclear ribonucleoprotein complexCellular ComponentTAS (11470819)
GO:0005515protein bindingMolecular FunctionIPI (11470819)
GO:0007000nucleolus organization and biogenesisBiological ProcessIDA (11424213)
Other Database Cross Links
NCBI Entrez Gene:70769