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Gene Information
Gene ID:13867
Full Name:v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Organism:Mus musculus (Mouse)
Genetic Location:10 D3|10 70.0 cM
Physical Location:128006423-128026556 on NC_000076.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2065    Symbol (Name): ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian))
Ortholog Status:The human GeneID 2065 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AI006228
Fold Change:-2.1, -1.7, -1.9, -1
Note:4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2
Dataset Information
Tissue:Whole brain
Phenotype:Acute ethanol response
Publication:Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_010153.1NP_034283.1NC_000076.5 range: 128006423..128026556, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0016324apical plasma membraneCellular ComponentIDA (15306553)
GO:0016328lateral plasma membraneCellular ComponentIDA (15306553)
GO:0016301kinase activityMolecular FunctionIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (11276227)
GO:0004872receptor activityMolecular FunctionIEA
GO:0004714transmembrane receptor protein tyrosine kinase activityMolecular FunctionIEA
GO:0004713protein-tyrosine kinase activityMolecular FunctionISO
GO:0004672protein kinase activityMolecular FunctionIEA
GO:0021545cranial nerve developmentBiological ProcessIMP (9338783)
GO:0014037Schwann cell differentiationBiological ProcessIMP (9338783)
GO:0007507heart developmentBiological ProcessIMP (9362461)
GO:0007422peripheral nervous system developmentBiological ProcessIMP (9362461)
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayBiological ProcessISO
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
GO:0043524negative regulation of neuron apoptosisBiological ProcessIMP (9338783)
Other Database Cross Links
NCBI Entrez Gene:13867