ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

2065

Symbol:

ERBB3

Full Name:

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

12q13

Physical Location:

54760158-54783394 on NC_000012.10

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 13867 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ERBB3

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001005915.1	NP_001005915.1	NC_000012.10 range: 54760158..54783394
NM_001982.2	NP_001973.2	NC_000012.10 range: 54760158..54783394

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0043235	receptor complex	Cellular Component	ISS (7514177)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (2687875)
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (11389077)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0016323	basolateral plasma membrane	Cellular Component	IDA (12646923)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0019838	growth factor binding	Molecular Function	IPI (11389077)
GO:0030296	protein tyrosine kinase activator activity	Molecular Function	IDA (7556068)
GO:0042803	protein homodimerization activity	Molecular Function	NAS (11389077)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0046982	protein heterodimerization activity	Molecular Function	IDA (10572067)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004888	transmembrane receptor activity	Molecular Function	ISS (7514177)
GO:0004714	transmembrane receptor protein tyrosine kinase activity	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IGI (7556068)
GO:0019838	growth factor binding	Molecular Function	ISS (7514177)
GO:0042127	regulation of cell proliferation	Biological Process	IDA (11389077)
GO:0042060	wound healing	Biological Process	NAS (12646923)
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade	Biological Process	TAS (17701904)
GO:0009968	negative regulation of signal transduction	Biological Process	IDA (11389077)
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	IGI (7556068)
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	IEA
GO:0007162	negative regulation of cell adhesion	Biological Process	IDA (7556068)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0051048	negative regulation of secretion	Biological Process	IDA (10559227)