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Gene Information
Gene ID:140608
Symbol:Atp5i
Full Name:ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e
Alias:Atp5k
Organism:Rattus norvegicus (Rat)
Chromosome:14
Genetic Location:14p22
Physical Location:1867343-1868471 on NC_005113.2
Gene Type:protein-coding
Human Ortholog:GeneID: 521    Symbol (Name): ATP5I (ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E)
Ortholog Status:The human GeneID 521 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Atp5i
Fold Change:-1.19
P Value:0.002
Note:Differential expression between ethanol and saccharin groups in amygdala
Dataset Information
Name:18405950
Method:Microarray
Tissue:Nucleus accumbens and amygdala
Phenotype:Ethanol self-administration, alcohol-preferring
Publication:Rodd et al. Pharmacol Biochem Behav. (2008) Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. PubMed
Summary:The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression kin the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats. Rats self-trained on a standard two-lever operant paradigm to administer either water-water, EtOH (15% v/v)-water, or saccharin (SAC; 0.0125% g/v)-water. For the ACB, there were 513 significant differences at the p < 0.01 level in named genes: 55 between SAC and water; 215 between EtOH and water, and 243 between EtOH and SAC. In the case of the AMYG (p < 0.01), there were 48 between SAC and water, 23 between EtOH and water, and 63 between EtOH and SAC group.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_080481.1NP_536729.1NC_005113.2 range: 1867343..1868471
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005739mitochondrionCellular ComponentIDA (1463732)
GO:0045263proton-transporting ATP synthase complex, coupling factor F(o)Cellular ComponentIEA
GO:0016469proton-transporting two-sector ATPase complexCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0005743mitochondrial inner membraneCellular ComponentIEA
GO:0005739mitochondrionCellular ComponentIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0046933hydrogen ion transporting ATP synthase activity, rotational mechanismMolecular FunctionIEA
GO:0046961hydrogen ion transporting ATPase activity, rotational mechanismMolecular FunctionIEA
GO:0015986ATP synthesis coupled proton transportBiological ProcessIEA
GO:0015992proton transportBiological ProcessIEA
GO:0006811ion transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:140608
RGD:621377
Ensembl:ENSRNOG00000000064
dbSNP:Atp5i