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Gene Information
Gene ID:14257
Symbol:Flt4
Full Name:FMS-like tyrosine kinase 4
Alias:AI323512|Chy|Flt-4|VEGFR-3|VEGFR3
Organism:Mus musculus (Mouse)
Chromosome:11
Genetic Location:11 A5-B1|11 25.0 cM
Physical Location:49423228-49465730 on NC_000077.5
Gene Type:protein-coding
Human Ortholog:GeneID: 2324    Symbol (Name): FLT4 (fms-related tyrosine kinase 4)
Ortholog Status:The human GeneID 2324 is also in human dataset(s).
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcw3Acute Alcohol Withdrawal112016-28 (cM)4.11.00E-05SignificantPARC
Caws4/Alcw3Chronic Alcohol Withdrawal11 15-36 (cM)6.72.00E-07SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_008029.2NP_032055.1NC_000077.5 range: 49423228..49465730
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0016021integral to membraneCellular ComponentRCA (12466851)
GO:0016020membraneCellular ComponentIEA
GO:0016740transferase activityMolecular FunctionIEA
GO:0016301kinase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (9247316|11279005)
GO:0005021vascular endothelial growth factor receptor activityMolecular FunctionISO
GO:0005021vascular endothelial growth factor receptor activityMolecular FunctionIGI (9247316)
GO:0004672protein kinase activityMolecular FunctionIEA
GO:0004713protein-tyrosine kinase activityMolecular FunctionIEA
GO:0004714transmembrane receptor protein tyrosine kinase activityMolecular FunctionIEA
GO:0004872receptor activityMolecular FunctionIEA
GO:0008284positive regulation of cell proliferationBiological ProcessISO
GO:0008284positive regulation of cell proliferationBiological ProcessIGI (9247316)
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
GO:0048010vascular endothelial growth factor receptor signaling pathwayBiological ProcessISO
Other Database Cross Links
NCBI Entrez Gene:14257
MGI:
Ensembl:ENSMUSG00000020357
dbSNP:Flt4
AceView:Flt4