Gene Information |
Gene ID: | | 14257 |
Symbol: | | Flt4 |
Full Name: | | FMS-like tyrosine kinase 4 |
Alias: | | AI323512|Chy|Flt-4|VEGFR-3|VEGFR3 |
Organism: | | Mus musculus (Mouse) |
Chromosome: | | 11 |
Genetic Location: | | 11 A5-B1|11 25.0 cM |
Physical Location: | | 49423228-49465730 on NC_000077.5 |
Gene Type: | | protein-coding |
Human Ortholog: | | GeneID: 2324 Symbol (Name): FLT4 (fms-related tyrosine kinase 4) |
Ortholog Status: | | The human GeneID 2324 is also in human dataset(s). |
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Gene in Ethanol Study Datasets |
QTL Information | QTL | Phenotype | Chr | Peak (cM) | LOD | P Value | Range | Status | QTL Link | |
Alcw3 | Acute Alcohol Withdrawal | 11 | 20 | 16-28 (cM) | 4.1 | 1.00E-05 | Significant | PARC | Caws4/Alcw3 | Chronic Alcohol Withdrawal | 11 | | 15-36 (cM) | 6.7 | 2.00E-07 | Significant | PARC |
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Gene Refseq Sequence Annotation |
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Gene Ontology (GO) Annotation |
GO ID | GO Term | Category | Evidence (PubMed) | |
GO:0005615 | extracellular space | Cellular Component | RCA (12466851) | |
GO:0016021 | integral to membrane | Cellular Component | RCA (12466851) | |
GO:0016020 | membrane | Cellular Component | IEA | |
GO:0016740 | transferase activity | Molecular Function | IEA | |
GO:0016301 | kinase activity | Molecular Function | IEA | |
GO:0000166 | nucleotide binding | Molecular Function | IEA | |
GO:0005524 | ATP binding | Molecular Function | IEA | |
GO:0005515 | protein binding | Molecular Function | IPI (9247316|11279005) | |
GO:0005021 | vascular endothelial growth factor receptor activity | Molecular Function | ISO | |
GO:0005021 | vascular endothelial growth factor receptor activity | Molecular Function | IGI (9247316) | |
GO:0004672 | protein kinase activity | Molecular Function | IEA | |
GO:0004713 | protein-tyrosine kinase activity | Molecular Function | IEA | |
GO:0004714 | transmembrane receptor protein tyrosine kinase activity | Molecular Function | IEA | |
GO:0004872 | receptor activity | Molecular Function | IEA | |
GO:0008284 | positive regulation of cell proliferation | Biological Process | ISO | |
GO:0008284 | positive regulation of cell proliferation | Biological Process | IGI (9247316) | |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | Biological Process | IEA | |
GO:0006468 | protein amino acid phosphorylation | Biological Process | IEA | |
GO:0048010 | vascular endothelial growth factor receptor signaling pathway | Biological Process | ISO | |
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Other Database Cross Links |
NCBI Entrez Gene: | | 14257 |
MGI: | |
Ensembl: | | ENSMUSG00000020357 |
dbSNP: | | Flt4 |
AceView: | | Flt4 |