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Gene Information
Gene ID:2324
Symbol:FLT4
Full Name:fms-related tyrosine kinase 4
Alias:FLT41|LMPH1A|PCL|VEGFR3
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q35.3
Physical Location:179961111-180009205 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 14257 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:FLT4
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002020.4NP_002011.2NC_000005.8 range: 179961111..180009205, complement
NM_182925.4NP_891555.2NC_000005.8 range: 179961111..180009205, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentTAS (8386825)
GO:0016740transferase activityMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (16530705)
GO:0005021vascular endothelial growth factor receptor activityMolecular FunctionIEA
GO:0005021vascular endothelial growth factor receptor activityMolecular FunctionIDA (9012504)
GO:0004872receptor activityMolecular FunctionIEA
GO:0004713protein-tyrosine kinase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0048010vascular endothelial growth factor receptor signaling pathwayBiological ProcessIDA (9012504)
GO:0008284positive regulation of cell proliferationBiological ProcessIGI (11574540)
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
GO:0048010vascular endothelial growth factor receptor signaling pathwayBiological ProcessIGI (11574540)
Other Database Cross Links
NCBI Entrez Gene:2324
HGNC:3767
Ensembl:ENSG00000037280
MIM:136352
HPRD:00636
HuGE Navigator:2324
dbSNP:FLT4
GeneCard:FLT4
AceView:FLT4