| Gene Information |
| Gene ID: | | 15018 |
| Symbol: | | H2-Q7 |
| Full Name: | | histocompatibility 2, Q region locus 7 |
| Alias: | | H-2Q7|Ped|Q9|Qa-2|Qa-7|Qa7 |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 17 |
| Genetic Location: | | 17 B1|17 19.19 cM |
| Physical Location: | | 35576160-35580587 on NC_000083.5 |
| Gene Type: | | protein-coding |
| Human Ortholog: | | This gene has no human ortholog. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | X05389 | | Fold Change: | | 1.7, 1.6 | | Note: | | ISS preferentially expressed gene. Two ratios of ISS/ILS are from cDNA array and RT-PCR. |
| | Gene Information | | Original ID1: | | X03210 | | Fold Change: | | 2.1, 1.6 | | Note: | | ISS preferentially expressed gene. Two ratios of ISS/ILS are from cDNA array and RT-PCR. |
| | Dataset Information | | Name: | | 11410715 | | Method: | | Microarray | | Tissue: | | Whole brain | | Phenotype: | | Ethanol sensitivity | | Publication: | | Xu et al. Alcohol Clin Exp Res. (2001) Comparison of global brain gene expression profiles between inbred long-sleep and inbred short-sleep mice by high-density gene array hybridization. PubMed | | Summary: | | Inbred long-sleep (ILS) and short-sleep (ISS) mice show significant central nervous system-mediated differences in sleep time for sedative dose of ethanol and are frequently used as a rodent model for ethanol sensitivity. In this study, we used both the gene discovery array (GDA) and the Mouse GEM 1 Microarray. Complex probes were prepared from total brain mRNA of ILS or ISS mice by using reverse transcription and 33P labeling. Differentially expressed genes identified from each method were confirmed by relative quantitative reverse transcription-polymerase chain reaction (RT-PCR). A total of 41 genes or expressed sequence tags (ESTs) display significant expression level differences between brains of ILS and ISS mice after GDA, GEM1 hybridization, and quantitative RTPCR confirmation. Among them, 18 clones were expressed higher in ILS mice, and 23 clones were expressed higher in ISS mice. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0016021 | integral to membrane | Cellular Component | IEA | |
| GO:0042612 | MHC class I protein complex | Cellular Component | IEA | |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | Biological Process | IEA | |
| GO:0006955 | immune response | Biological Process | IEA | |
| GO:0019882 | antigen processing and presentation | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 15018 |
| MGI: | |
| Ensembl: | | ENSMUSG00000060550 |
| dbSNP: | | H2-Q7 |
| AceView: | | H2-Q7 |
