ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

15242

Symbol:

Hhex

Full Name:

hematopoietically expressed homeobox

Alias:

Hex|Hhex-rs2|Prh|Prhx

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

19 D1|19 47.5 cM

Physical Location:

37509330-37515220 on NC_000085.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3087 Symbol (Name): HHEX (hematopoietically expressed homeobox)

Ortholog Status:

The human GeneID 3087 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw2/Alcdp2	Chronic Alcohol Withdrawal	19	47	36.5-ter (cM)	5.3	6.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008245.3	NP_032271.1	NC_000085.5 range: 37509330..37515220

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IDA (11044484)
GO:0016564	transcription repressor activity	Molecular Function	IDA (10804173)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0030154	cell differentiation	Biological Process	IEA
GO:0030177	positive regulation of Wnt receptor signaling pathway	Biological Process	IMP (16936074)
GO:0030878	thyroid gland development	Biological Process	IMP (10804184\|15581879)
GO:0030900	forebrain development	Biological Process	IMP (10804184\|11291863\|15459110)
GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	Biological Process	IDA (12588764)
GO:0035050	embryonic heart tube development	Biological Process	IMP (15459110)
GO:0042127	regulation of cell proliferation	Biological Process	IMP (14736744)
GO:0001889	liver development	Biological Process	IMP (10804184\|15459110)
GO:0016525	negative regulation of angiogenesis	Biological Process	IDA (12588764)
GO:0016055	Wnt receptor signaling pathway	Biological Process	IEA
GO:0010553	negative regulation of specific transcription from RNA polymerase II promoter	Biological Process	IDA (12588764)
GO:0009952	anterior/posterior pattern formation	Biological Process	IMP (16936074)
GO:0009887	organ morphogenesis	Biological Process	IMP (14736744)
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0045449	regulation of transcription	Biological Process	IEA