ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Idh1

Full Name:

isocitrate dehydrogenase 1 (NADP+), soluble

Alias:

AI314845|AI788952|E030024J03Rik|Id-1|Idh-1|Idpc|MGC115782

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 C2|1 29.8 cM

Physical Location:

65205201-65225687 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3417 Symbol (Name): IDH1 (isocitrate dehydrogenase 1 (NADP+), soluble)

Ortholog Status:

The human GeneID 3417 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws1/Alcw5	Chronic Alcohol Withdrawal	1		28-47 (cM)	6.5	3.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010497.3	NP_034627.3	NC_000067.5 range: 65205201..65225687, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005829	cytosol	Cellular Component	IDA (12031902)
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0030145	manganese ion binding	Molecular Function	IEA
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0004450	isocitrate dehydrogenase (NADP+) activity	Molecular Function	IDA (1180875\|1914521\|12031902)
GO:0006979	response to oxidative stress	Biological Process	IDA (12031902)
GO:0008152	metabolic process	Biological Process	IEA
GO:0006099	tricarboxylic acid cycle	Biological Process	IEA
GO:0006097	glyoxylate cycle	Biological Process	IEA
GO:0006749	glutathione metabolic process	Biological Process	IMP (12031902)