ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Il10

Full Name:

interleukin 10

Alias:

CSIF|Il-10

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 E4|1 69.9 cM

Physical Location:

132916423-132921546 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3586 Symbol (Name): IL10 (interleukin 10)

Ortholog Status:

The human GeneID 3586 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010548.1	NP_034678.1	NC_000067.5 range: 132916423..132921546

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (10545106\|10899905\|15220916\|15240714\|16275384\|17137799)
GO:0005125	cytokine activity	Molecular Function	IDA (11027433)
GO:0005125	cytokine activity	Molecular Function	IMP (15240714)
GO:0002904	positive regulation of B cell apoptosis	Biological Process	ISS (9184696)
GO:0042742	defense response to bacterium	Biological Process	IDA (10899905)
GO:0032695	negative regulation of interleukin-12 production	Biological Process	IMP (15240714)
GO:0030889	negative regulation of B cell proliferation	Biological Process	ISS (9184696)
GO:0030886	negative regulation of myeloid dendritic cell activation	Biological Process	IMP (15240714)
GO:0010468	regulation of gene expression	Biological Process	ISS (9184696)
GO:0006955	immune response	Biological Process	IEA
GO:0045348	positive regulation of MHC class II biosynthetic process	Biological Process	IDA (11027433)