ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Il18

Full Name:

interleukin 18

Alias:

Igif|Il-18

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 A5.3|9 29.0 cM

Physical Location:

50373472-50389941 on NC_000075.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3606 Symbol (Name): IL18 (interleukin 18 (interferon-gamma-inducing factor))

Ortholog Status:

The human GeneID 3606 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap5q	Alcohol Preference Drinking	9	25	10-35 (cM)	4.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008360.1	NP_032386.1	NC_000075.5 range: 50373472..50389941

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (15220916)
GO:0005125	cytokine activity	Molecular Function	IEA
GO:0005149	interleukin-1 receptor binding	Molecular Function	IEA
GO:0001525	angiogenesis	Biological Process	ISS (11466388)
GO:0042104	positive regulation of activated T cell proliferation	Biological Process	ISS (8766574)
GO:0042095	interferon-gamma biosynthetic process	Biological Process	IMP (11907086)
GO:0042088	T-helper 1 type immune response	Biological Process	ISS (8766574)
GO:0030431	sleep	Biological Process	ISS (11506998)
GO:0030155	regulation of cell adhesion	Biological Process	ISS (11477102)
GO:0008625	induction of apoptosis via death domain receptors	Biological Process	TAS (11714750)
GO:0006955	immune response	Biological Process	TAS (12048345)
GO:0042231	interleukin-13 biosynthetic process	Biological Process	TAS (11716531)