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Gene Information
Gene ID:3606
Symbol:IL18
Full Name:interleukin 18 (interferon-gamma-inducing factor)
Alias:IGIF|IL-18|IL-1g|IL1F4|MGC12320
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11q22.2-q22.3
Physical Location:111519185-111540049 on NC_000011.8, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 16173 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:IL18
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001562.2NP_001553.1NC_000011.8 range: 111519185..111540049, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005576extracellular regionCellular ComponentTAS (11598150)
GO:0005615extracellular spaceCellular ComponentIEA
GO:0004871signal transducer activityMolecular FunctionTAS (8999896)
GO:0005149interleukin-1 receptor bindingMolecular FunctionIEA
GO:0001525angiogenesisBiological ProcessIDA (11466388)
GO:0042092T-helper 2 type immune responseBiological ProcessTAS (11905033)
GO:0042094interleukin-2 biosynthetic processBiological ProcessTAS (10653850)
GO:0042095interferon-gamma biosynthetic processBiological ProcessTAS (10227975)
GO:0042104positive regulation of activated T cell proliferationBiological ProcessIDA (8766574|10000000)
GO:0042231interleukin-13 biosynthetic processBiological ProcessTAS (10227975)
GO:0042088T-helper 1 type immune responseBiological ProcessIDA (8766574)
GO:0042033chemokine biosynthetic processBiological ProcessTAS (11598150)
GO:0030431sleepBiological ProcessISS (11506998)
GO:0030155regulation of cell adhesionBiological ProcessIDA (11477102)
GO:0007267cell-cell signalingBiological ProcessTAS (9792649)
GO:0006955immune responseBiological ProcessTAS (8999896)
GO:0006955immune responseBiological ProcessIEA
GO:0042253granulocyte macrophage colony-stimulating factor biosynthetic processBiological ProcessTAS (10653850)
Other Database Cross Links
NCBI Entrez Gene:3606
HGNC:5986
Ensembl:
MIM:600953
HPRD:02976
HuGE Navigator:3606
dbSNP:IL18
GeneCard:IL18
AceView:IL18