ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Lepr

Full Name:

leptin receptor

Alias:

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 C6|4 46.7 cM

Physical Location:

101390043-101487909 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3953 Symbol (Name): LEPR (leptin receptor)

Ortholog Status:

The human GeneID 3953 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws2	Chronic Alcohol Withdrawal	4		33-51 (cM)	2.3	0.005	Significant	PARC

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (9102398)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (9102398\|15520383)
GO:0004896	hematopoietin/interferon-class (D200-domain) cytokine receptor activity	Molecular Function	IEA
GO:0004888	transmembrane receptor activity	Molecular Function	TAS (9102398)
GO:0007165	signal transduction	Biological Process	TAS (9102398)
GO:0008203	cholesterol metabolic process	Biological Process	IGI (15995171)
GO:0019222	regulation of metabolic process	Biological Process	TAS (9102398)
GO:0051346	negative regulation of hydrolase activity	Biological Process	IGI (15995171)