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Gene Information
Gene ID:3953
Symbol:LEPR
Full Name:leptin receptor
Alias:CD295|OBR
Organism:Homo sapiens (Human)
Chromosome:1
Genetic Location:1p31
Physical Location:65658905-65875409 on NC_000001.9
Gene Type:protein-coding
Orthologs:This gene has Mouse: 16847 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:LEPR
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001003679.1NP_001003679.1NC_000001.9 range: 65658905..65875409
NM_001003680.1NP_001003680.1NC_000001.9 range: 65658905..65875409
NM_002303.3NP_002294.2NC_000001.9 range: 65658905..65875409
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentNR
GO:0004896hematopoietin/interferon-class (D200-domain) cytokine receptor activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (11279102)
GO:0006112energy reserve metabolic processBiological ProcessTAS (9537324)
GO:0007166cell surface receptor linked signal transductionBiological ProcessTAS (9537324)
GO:0007275multicellular organismal developmentBiological ProcessTAS (9537324)
Other Database Cross Links
NCBI Entrez Gene:3953
HGNC:6554
Ensembl:ENSG00000116678
MIM:601007
HPRD:03001
HuGE Navigator:3953
dbSNP:LEPR
GeneCard:LEPR
AceView:LEPR