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Gene Information
Gene ID:170729
Symbol:Scrt1
Full Name:scratch homolog 1, zinc finger protein (Drosophila)
Organism:Mus musculus (Mouse)
Chromosome:15
Genetic Location:15 E1
Physical Location:76346632-76352558 on NC_000081.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 83482    Symbol (Name): SCRT1 (scratch homolog 1, zinc finger protein (Drosophila))
Ortholog Status:The human GeneID 83482 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Scrt1
Fold Change:2.4
Note:More highly expressed in ILS
Dataset Information
Name:16465594
Method:Microarray and QTL
Tissue:Cerebellum
Phenotype:Ethanol sensitivity
Publication:MacLaren et al. Mamm Genome. (2006) Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. PubMed
Summary:The Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) mouse strains have a 16-fold difference in duration of loss of the righting response (LORR) following administration of a sedative dose of ethanol. Four quantitative trait loci (QTLs) have been mapped in these strains for this trait. Genome-wide expression profiling in cerebellum was used here to identify candidate genes for regulatory region differences in these two strains. Fifteen differentially expressed genes were found that map to the QTL regions.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_130893.3NP_570963.1NC_000081.5 range: 76346632..76352558, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005634nucleusCellular ComponentIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0003677DNA bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006350transcriptionBiological ProcessIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:170729
MGI:
Ensembl:ENSMUSG00000048385
dbSNP:Scrt1
AceView:Scrt1