ERGR - Ethanol-Related Gene Resource

Dataset Description

Dataset Name: 16465594

Species: Mouse

No. of Genes: 15

Tissue: Cerebellum

Phenotype: Ethanol sensitivity

Publication: MacLaren et al. Mamm Genome. (2006) Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. PubMed

Dataset Summary: The Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) mouse strains have a 16-fold difference in duration of loss of the righting response (LORR) following administration of a sedative dose of ethanol. Four quantitative trait loci (QTLs) have been mapped in these strains for this trait. Genome-wide expression profiling in cerebellum was used here to identify candidate genes for regulatory region differences in these two strains. Fifteen differentially expressed genes were found that map to the QTL regions.

Gene list of this dataset (15 genes)

GeneID Symbol Name Genetic location Original ID1 Original ID2
18549 Pcsk2 proprotein convertase subtilisin/kexin type 2 2 F3-H2|2 81.4 cM Pcsk2
30805 Slc22a4 solute carrier family 22 (organic cation transporter), member 4 11 B1.3|11 28.0 cM Slc22a4
BG075643
338367 Myo1d myosin ID 11 B5|11 46.0 cM Myo1d
68588 Cthrc1 collagen triple helix repeat containing 1 15 C Cthrc1
16691 Krt8 keratin 8 15 F3|15 58.86 cM Krt2-8
107753 Lgals2 lectin, galactose-binding, soluble 2 15 E1 Lgals2
170729 Scrt1 scratch homolog 1, zinc finger protein (Drosophila) 15 E1 Scrt1
22596 Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 1 E|1 42.0 cM Xrcc5
215653 Rassf2 Ras association (RalGDS/AF-6) domain family member 2 2 F2 Rassf2
13591 Ebf1 early B-cell factor 1 11 B1.1|11 20.0 cM Ebf1
55943 Stx8 syntaxin 8 11 B3 Stx8
76281 Tax1bp3 Tax1 (human T-cell leukemia virus type I) binding protein 3 11 B4 Tax1bp3
21927 Tnfaip1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 11 B5|11 45.1 cM Tnfaip1
11908 Atf1 activating transcription factor 1 - Atf1

GeneID	Symbol	Name	Genetic location	Original ID1	Original ID2
18549	Pcsk2	proprotein convertase subtilisin/kexin type 2	2 F3-H2\|2 81.4 cM	Pcsk2
30805	Slc22a4	solute carrier family 22 (organic cation transporter), member 4	11 B1.3\|11 28.0 cM	Slc22a4
				BG075643
338367	Myo1d	myosin ID	11 B5\|11 46.0 cM	Myo1d
68588	Cthrc1	collagen triple helix repeat containing 1	15 C	Cthrc1
16691	Krt8	keratin 8	15 F3\|15 58.86 cM	Krt2-8
107753	Lgals2	lectin, galactose-binding, soluble 2	15 E1	Lgals2
170729	Scrt1	scratch homolog 1, zinc finger protein (Drosophila)	15 E1	Scrt1
22596	Xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5	1 E\|1 42.0 cM	Xrcc5
215653	Rassf2	Ras association (RalGDS/AF-6) domain family member 2	2 F2	Rassf2
13591	Ebf1	early B-cell factor 1	11 B1.1\|11 20.0 cM	Ebf1
55943	Stx8	syntaxin 8	11 B3	Stx8
76281	Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	11 B4	Tax1bp3
21927	Tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	11 B5\|11 45.1 cM	Tnfaip1
11908	Atf1	activating transcription factor 1	-	Atf1