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Gene Information
Gene ID:76281
Symbol:Tax1bp3
Full Name:Tax1 (human T-cell leukemia virus type I) binding protein 3
Alias:1300011C24Rik|TIP-1
Organism:Mus musculus (Mouse)
Chromosome:11
Genetic Location:11 B4
Physical Location:72990584-72995547 on NC_000077.5
Gene Type:protein-coding
Human Ortholog:GeneID: 30851    Symbol (Name): TAX1BP3 (Tax1 (human T-cell leukemia virus type I) binding protein 3)
Ortholog Status:The human GeneID 30851 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Tax1bp3
Fold Change:2.2
Note:More highly expressed in ISS
Dataset Information
Name:16465594
Method:Microarray and QTL
Tissue:Cerebellum
Phenotype:Ethanol sensitivity
Publication:MacLaren et al. Mamm Genome. (2006) Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. PubMed
Summary:The Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) mouse strains have a 16-fold difference in duration of loss of the righting response (LORR) following administration of a sedative dose of ethanol. Four quantitative trait loci (QTLs) have been mapped in these strains for this trait. Genome-wide expression profiling in cerebellum was used here to identify candidate genes for regulatory region differences in these two strains. Fifteen differentially expressed genes were found that map to the QTL regions.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_029564.2NP_083840.1NC_000077.5 range: 72990584..72995547
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIDA (12874278)
GO:0005737cytoplasmCellular ComponentIDA (12874278)
GO:0005515protein bindingMolecular FunctionIEA
GO:0008013beta-catenin bindingMolecular FunctionIPI (12874278)
GO:0030528transcription regulator activityMolecular FunctionIMP (12874278)
GO:0008285negative regulation of cell proliferationBiological ProcessIDA (12874278)
GO:0016055Wnt receptor signaling pathwayBiological ProcessIEA
GO:0030178negative regulation of Wnt receptor signaling pathwayBiological ProcessIDA (12874278)
Other Database Cross Links
NCBI Entrez Gene:76281
MGI:
Ensembl:ENSMUSG00000040158
dbSNP:Tax1bp3
AceView:Tax1bp3