ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Rassf2

Full Name:

Ras association (RalGDS/AF-6) domain family member 2

Alias:

3830431H01Rik|9030412M04Rik|AI852669|AW495050

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 F2

Physical Location:

131818585-131855545 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9770 Symbol (Name): RASSF2 (Ras association (RalGDS/AF-6) domain family member 2)

Ortholog Status:

The human GeneID 9770 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		16465594
Method:		Microarray and QTL
Tissue:		Cerebellum
Phenotype:		Ethanol sensitivity
Publication:		MacLaren et al. Mamm Genome. (2006) Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. PubMed
Summary:		The Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) mouse strains have a 16-fold difference in duration of loss of the righting response (LORR) following administration of a sedative dose of ethanol. Four quantitative trait loci (QTLs) have been mapped in these strains for this trait. Genome-wide expression profiling in cerebellum was used here to identify candidate genes for regulatory region differences in these two strains. Fifteen differentially expressed genes were found that map to the QTL regions.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_175445.3	NP_780654.1	NC_000068.6 range: 131818585..131855545, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005515	protein binding	Molecular Function	IEA
GO:0007049	cell cycle	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	IEA
GO:0007218	neuropeptide signaling pathway	Biological Process	RCA (12466851)
GO:0045786	negative regulation of cell cycle	Biological Process	IEA