ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Tnfaip1

Full Name:

tumor necrosis factor, alpha-induced protein 1 (endothelial)

Alias:

Edp-1|Edp1|Tnfip1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B5|11 45.1 cM

Physical Location:

78336349-78349695 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 7126 Symbol (Name): TNFAIP1 (tumor necrosis factor, alpha-induced protein 1 (endothelial))

Ortholog Status:

The human GeneID 7126 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		16465594
Method:		Microarray and QTL
Tissue:		Cerebellum
Phenotype:		Ethanol sensitivity
Publication:		MacLaren et al. Mamm Genome. (2006) Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. PubMed
Summary:		The Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) mouse strains have a 16-fold difference in duration of loss of the righting response (LORR) following administration of a sedative dose of ethanol. Four quantitative trait loci (QTLs) have been mapped in these strains for this trait. Genome-wide expression profiling in cerebellum was used here to identify candidate genes for regulatory region differences in these two strains. Fifteen differentially expressed genes were found that map to the QTL regions.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009395.3	NP_033421.2	NC_000077.5 range: 78336349..78349695, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0008076	voltage-gated potassium channel complex	Cellular Component	RCA (16141072)
GO:0016020	membrane	Cellular Component	RCA (16141072)
GO:0005249	voltage-gated potassium channel activity	Molecular Function	RCA (16141072)
GO:0005515	protein binding	Molecular Function	RCA (16141072)
GO:0006813	potassium ion transport	Biological Process	RCA (16141072)
GO:0009790	embryonic development	Biological Process	IEP (1370465)