ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Stx8

Full Name:

syntaxin 8

Alias:

0610007H08Rik|1110002H11Rik|4930571E13Rik|CARB

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B3

Physical Location:

67779984-68020649 on NC_000077.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 9482 Symbol (Name): STX8 (syntaxin 8)

Ortholog Status:

The human GeneID 9482 is also in human dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		16465594
Method:		Microarray and QTL
Tissue:		Cerebellum
Phenotype:		Ethanol sensitivity
Publication:		MacLaren et al. Mamm Genome. (2006) Expression profiling identifies novel candidate genes for ethanol sensitivity QTLs. PubMed
Summary:		The Inbred Long Sleep (ILS) and Inbred Short Sleep (ISS) mouse strains have a 16-fold difference in duration of loss of the righting response (LORR) following administration of a sedative dose of ethanol. Four quantitative trait loci (QTLs) have been mapped in these strains for this trait. Genome-wide expression profiling in cerebellum was used here to identify candidate genes for regulatory region differences in these two strains. Fifteen differentially expressed genes were found that map to the QTL regions.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_018768.2	NP_061238.1	NC_000077.5 range: 67779984..68020649

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0005484	SNAP receptor activity	Molecular Function	IEA
GO:0006810	transport	Biological Process	RCA (12466851)
GO:0006886	intracellular protein transport	Biological Process	IEA