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Gene Information
Gene ID:9482
Symbol:STX8
Full Name:syntaxin 8
Alias:CARB
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17p12
Physical Location:9094512-9419999 on NC_000017.9, complement
Gene Type:protein-coding
Orthologs:This gene has Mouse: 55943 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S1852  10456226
Region:8456226-12456226
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_004853.1NP_004844.1NC_000017.9 range: 9094512..9419999, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005783endoplasmic reticulumCellular ComponentTAS (9852078)
GO:0005887integral to plasma membraneCellular ComponentTAS (10198254)
GO:0016020membraneCellular ComponentIEA
GO:0006810transportBiological ProcessTAS (10198254)
Other Database Cross Links
NCBI Entrez Gene:9482
HGNC:11443
Ensembl:ENSG00000170310
MIM:604203
HPRD:05012
HuGE Navigator:9482
dbSNP:STX8
GeneCard:STX8
AceView:STX8