ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mlph

Full Name:

melanophilin

Alias:

2210418F23Rik|5031433I09Rik|AW228792|D1Wsu84e|Slac-2a|l(1)-3Rk|l1Rk3|ln

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 D|1 59.0 cM

Physical Location:

92811683-92846335 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 79083 Symbol (Name): MLPH (melanophilin)

Ortholog Status:

The human GeneID 79083 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_053015.2	NP_443748.2	NC_000067.5 range: 92811683..92846335

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042470	melanosome	Cellular Component	TAS (11856727\|12221080)
GO:0042470	melanosome	Cellular Component	IDA (11887186\|14730011\|16137617)
GO:0015629	actin cytoskeleton	Cellular Component	IDA (12221080)
GO:0003779	actin binding	Molecular Function	IDA (12221080)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0031489	myosin V binding	Molecular Function	IPI (11887186\|14730011)
GO:0051010	microtubule plus-end binding	Molecular Function	IPI (16137617)
GO:0017137	Rab GTPase binding	Molecular Function	IDA (11856727)
GO:0017022	myosin binding	Molecular Function	IDA (11856727)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (11773082)
GO:0032400	melanosome localization	Biological Process	IMP (11886590\|11887186\|14730011)
GO:0006886	intracellular protein transport	Biological Process	IEA
GO:0006605	protein targeting	Biological Process	IMP (11886590\|11887186)
GO:0043473	pigmentation	Biological Process	IMP (2379821\|17247639)
GO:0030318	melanocyte differentiation	Biological Process	IMP (2379821\|11504925)