ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mthfr

Full Name:

5,10-methylenetetrahydrofolate reductase

Alias:

AI323986

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 E2|4 76.4 cM

Physical Location:

147415330-147433657 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4524 Symbol (Name): MTHFR (5,10-methylenetetrahydrofolate reductase (NADPH))

Ortholog Status:

The human GeneID 4524 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010840.2	NP_034970.2	NC_000070.5 range: 147415330..147433657

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0003824	catalytic activity	Molecular Function	IEA
GO:0004489	methylenetetrahydrofolate reductase (NADPH) activity	Molecular Function	IMP (15217352)
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0006555	methionine metabolic process	Biological Process	IEA
GO:0009086	methionine biosynthetic process	Biological Process	IMP (15217352)