ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

17869

Symbol:

Myc

Full Name:

myelocytomatosis oncogene

Alias:

AU016757|Myc2|Niard|Nird|c-myc

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 D2-D3|15 32.0 cM

Physical Location:

61816895-61821915 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4609 Symbol (Name): MYC (v-myc myelocytomatosis viral oncogene homolog (avian))

Ortholog Status:

The human GeneID 4609 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010849.4	NP_034979.3	NC_000081.5 range: 61816895..61821915

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	ISS (15994933)
GO:0016604	nuclear body	Cellular Component	IDA (15735755)
GO:0005819	spindle	Cellular Component	IDA (15509711)
GO:0005634	nucleus	Cellular Component	IDA (11872843\|17631878)
GO:0005515	protein binding	Molecular Function	ISS (15994933)
GO:0005515	protein binding	Molecular Function	IPI (10229200\|15735755\|17382917)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IDA (12970171\|14560010)
GO:0030528	transcription regulator activity	Molecular Function	IEA
GO:0042127	regulation of cell proliferation	Biological Process	IDA (12235125\|14517295)
GO:0042474	middle ear morphogenesis	Biological Process	IMP (17523175)
GO:0001783	B cell apoptosis	Biological Process	IMP (12970677)
GO:0016485	protein processing	Biological Process	IMP (12970677)
GO:0042981	regulation of apoptosis	Biological Process	IDA (12235125)
GO:0043085	positive regulation of catalytic activity	Biological Process	IMP (17382917)
GO:0043279	response to alkaloid	Biological Process	IMP (12970677)
GO:0043473	pigmentation	Biological Process	IMP (17523175)
GO:0045449	regulation of transcription	Biological Process	IGI (8521822)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (17382917)
GO:0048705	skeletal morphogenesis	Biological Process	IMP (17523175)
GO:0010468	regulation of gene expression	Biological Process	IDA (11438662)
GO:0009314	response to radiation	Biological Process	IMP (14517295)
GO:0009314	response to radiation	Biological Process	IDA (14517295)
GO:0001836	release of cytochrome c from mitochondria	Biological Process	IDA (14517295)
GO:0006309	DNA fragmentation during apoptosis	Biological Process	IDA (14517295)
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006919	caspase activation	Biological Process	IDA (14517295)
GO:0008284	positive regulation of cell proliferation	Biological Process	ISS (15994933)
GO:0008629	induction of apoptosis by intracellular signals	Biological Process	IDA (14517295)
GO:0008629	induction of apoptosis by intracellular signals	Biological Process	IMP (14517295)
GO:0008633	activation of pro-apoptotic gene products	Biological Process	IDA (14517295)
GO:0008633	activation of pro-apoptotic gene products	Biological Process	IMP (14517295)
GO:0008634	negative regulation of survival gene product expression	Biological Process	IDA (14517295)
GO:0008634	negative regulation of survival gene product expression	Biological Process	IMP (14517295)
GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	Biological Process	IMP (17523175)