ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nek1

Full Name:

NIMA (never in mitosis gene a)-related expressed kinase 1

Alias:

D8Ertd790e|kat

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 B3.1|8 32.0 cM

Physical Location:

63472016-63609030 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4750 Symbol (Name): NEK1 (NIMA (never in mitosis gene a)-related kinase 1)

Ortholog Status:

The human GeneID 4750 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_175089.3	NP_780298.2	NC_000074.5 range: 63472016..63609030

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	ISS (15604234)
GO:0005737	cytoplasm	Cellular Component	ISS (15604234)
GO:0016301	kinase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	ISS (15604234)
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0010212	response to ionizing radiation	Biological Process	IMP (15604234)
GO:0007067	mitosis	Biological Process	IEA
GO:0007049	cell cycle	Biological Process	IEA
GO:0006974	response to DNA damage stimulus	Biological Process	IMP (15604234)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0051301	cell division	Biological Process	IEA