ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Pemt

Full Name:

phosphatidylethanolamine N-methyltransferase

Alias:

AI255394|Pempt|Pempt2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

11 B1.3|11 31.0 cM

Physical Location:

59784118-59850340 on NC_000077.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10400 Symbol (Name): PEMT (phosphatidylethanolamine N-methyltransferase)

Ortholog Status:

The human GeneID 10400 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws4/Alcw3	Chronic Alcohol Withdrawal	11		15-36 (cM)	6.7	2.00E-07	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008819.2	NP_032845.2	NC_000077.5 range: 59784118..59850340, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0005740	mitochondrial envelope	Cellular Component	TAS (8978486)
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0005789	endoplasmic reticulum membrane	Cellular Component	IDA (12072432)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0004608	phosphatidylethanolamine N-methyltransferase activity	Molecular Function	ISS (8978486)
GO:0008170	N-methyltransferase activity	Molecular Function	IEA
GO:0008168	methyltransferase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008654	phospholipid biosynthetic process	Biological Process	IEA
GO:0006644	phospholipid metabolic process	Biological Process	IEA
GO:0006656	phosphatidylcholine biosynthetic process	Biological Process	ISS (8978486)