ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Pik3r2

Full Name:

phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 B3.3|8 33.5 cM

Physical Location:

73292077-73300579 on NC_000074.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5296 Symbol (Name): PIK3R2 (phosphoinositide-3-kinase, regulatory subunit 2 (beta))

Ortholog Status:

The human GeneID 5296 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_008841.1	NP_032867.1	NC_000074.5 range: 73292077..73300579, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005942	phosphoinositide 3-kinase complex	Cellular Component	NAS (14504291)
GO:0005515	protein binding	Molecular Function	IPI (15102471)
GO:0035014	phosphoinositide 3-kinase regulator activity	Molecular Function	IEA
GO:0016303	1-phosphatidylinositol-3-kinase activity	Molecular Function	IMP (14504291)
GO:0016301	kinase activity	Molecular Function	IEA
GO:0008286	insulin receptor signaling pathway	Biological Process	NAS (14504291)
GO:0019987	negative regulation of anti-apoptosis	Biological Process	IMP (14504291)
GO:0007165	signal transduction	Biological Process	IEA
GO:0042325	regulation of phosphorylation	Biological Process	NAS (14504291)